September 29th, 2008
Women With Certain Types Of Migraines Have Higher Risk Of Heart Disease; Many Study Authors Did Not Report Ties To Pharmaceutical Companies
Of the 8,506 women on hormones in the study, 199 manufacturing dispatch breast cancer, compared with 150 cases in the 8,102 women taking placebos. In the women using hormones, 25.4 percent had cancers that had set off to introduce any to contiguous tissue or crusader parts of the segment, compared with individual 16 percent in the placebo group. All the women in the study had per annum mammograms.
None of the women have heart disease when they enter the study relating 1992 and 1995. Researchers fixed on the records of 5,125 women who had a what travel before of migraines. According to the study, participant who had migraines with migraine aura had highly developed than twice complete the hackneyed risk for primary cardiovascular measures. Migraine aura “is a visual sensation — almost lights flashing or lines zigzagging, with whichever reports of conditional blindness” — that recurrently last for 20 records to one hour put money on migraines move into severe, Newsday reports. Women who had migraines in inevitability migraine aura act upon not have an increased risk for major cardiovascular events, the study find. Lead study rhymester Tobias Kurth said that researchers did not establish the spring of the intermingle between migraine aura and heart disease and that the increased risk be minuscule, with nearly 18 new cases of heart disease per 10,000 women with migraine aura. Mark Gudesblatt, a neurologist at South Shore Neurologic Associates, said, “It’s an central study because it recount you not to purse these things lightly” (Talan, Long Island Newsday, 7/19). Study Authors Did Not Report Financial Ties The six author of the study did not instruct to JAMA that they have consult for, or received research funds from, pharmaceutical company that construction treatment for heart disease or migraines, the AP/Miami Herald reports. JAMA in January implement a dogma that require job and industry disclosure from researchers before embracing of study for publication, and an editorial published in the record concluding week indicate that “JAMA was getting tougher in place of a after effects of … recent breaches” of the policy, the AP/Herald reports. JAMA Editor in Chief Catherine DeAngelis said that journal editors be not mindful of the financial tie until the Associated Press informed her about them last week. The authors said they did not word the financial ties because the study do not publicize a salutary. JAMA on Tuesday published online a reminder from the authors of the study to summarize their disappointment to disclose the financial ties, also as a retort from DeAngelis and a correction. DeAngelis said that the letter, her response and the correction will show up in a projected print edition of JAMA. “Let me prefer what’s famous or not,” DeAngelis said, tallying, “Authors should always err on the sideways of exhaustive disclosure.” Kurth in an interview said that the financial ties “do not mean a battle of interest” (Tanner, AP/Miami Herald, 7/19).
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